Division of Epidemiology, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China. Department of Medicine & Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China. MRC Integrative Epidemiology Unit, Bristol Population Health Science Institute, The University of Bristol, United Kingdom. Division of Epidemiology, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China; SH Big Data Decision Analytics Research Centre, The Chinese University of Hong Kong, Hong Kong, China. Electronic address: kelvintsoi@cuhk.edu.hk.